Article
High degree of conservation in the hepatitis B virus core gene during the immune tolerant phase in perinatally acquired chronic hepatitis B virus infection.
Journal of hepatology - 1 Mar 1997
Bozkaya H, Akarca U S, Ayola B, Lok A S
Abstract excerpt
BACKGROUND: Mutations in the hepatitis B virus genome have been implicated in the persistence of hepatitis B virus infection and the pathogenesis of hepatitis B virus related liver disease. In view of the heterogeneity in published sequences, data from cross-sectional studies of unrelated subject...
Topics
- Adolescent
- Adult
- Base Sequence
- Child
- Child, Preschool
- Chronic Disease
- Consensus Sequence
- Cross-Sectional Studies
- DNA, Viral
- Female
- Gene Frequency
- Genes, Viral
- Hepatitis B
- Hepatitis B Core Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Infectious Disease Transmission, Vertical