Article
Hepatitis B virus variants with core gene deletions in the evolution of chronic hepatitis B infection.
Gastroenterology - 1 Jul 1996
Marinos G, Torre F, Günther S, Thomas M G, Will H, Williams R, Naoumov N V
Abstract excerpt
BACKGROUND & AIMS: Genomic variants of the hepatitis B virus (HBV) with core gene deletions have been identified in patients with chronic active hepatitis B, but the significance of these mutations in the course of chronic HBV infection remains unknown. The aim of this study was to longitudinally...
Topics
- Adult
- Aged
- Base Sequence
- Chronic Disease
- Female
- Gene Deletion
- Genes, Viral
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Interferon alpha-2
- Interferon-alpha
- Longitudinal Studies
- Male
- Middle Aged
- Molecular Sequence Data