Article
Hepatitis B virus (HBV) genomic variations in chronic hepatitis.
Archives of virology. Supplementum - 1 Jan 1992
Cariani E, Fiordalisi G, Primi D
Abstract excerpt
Using PCR we have examined the sequence of the pre-C/C region of HBV from sera of anti-HBe positive, chronically HBV-infected patients. The large majority of sera tested contained a mixture of heterogeneous pre-C sequences with 1-3 non-randomly located point mutations. Some of the resultant varia...
Topics
- Base Sequence
- Carrier State
- Chronic Disease
- DNA, Viral
- Genetic Variation
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Core Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Molecular Sequence Data
- Mutagenesis
- Protein Precursors
