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Article

Hepatitis B virus (HBV) genomic variations in chronic hepatitis.

Archives of virology. Supplementum - 1 Jan 1992

Cariani E, Fiordalisi G, Primi D

Abstract excerpt

Using PCR we have examined the sequence of the pre-C/C region of HBV from sera of anti-HBe positive, chronically HBV-infected patients. The large majority of sera tested contained a mixture of heterogeneous pre-C sequences with 1-3 non-randomly located point mutations. Some of the resultant variant viruses are incapable of synthesizing immunogenic proteins and may be involved in viral persistence in chronic...

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Identifiers

PMID: 1450730
DOI: 10.1007/978-3-7091-5633-9_18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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