Article
Familial clustering of HBV pre-C and pre-S mutants.
Journal of hepatology - 1 Feb 1997
Santantonio T, Jung M C, Pastore G, Angarano G, Günther S, Will H
Abstract excerpt
BACKGROUND/AIMS: Little is known about the persistence and risk of infection with hepatitis B viruses (HBV) containing mutations in the pre-C and pre-S region. The aim of this study was to study the long-term persistence and the risk of intrafamilial spreading of these variants. METHODS: Serological markers were analyzed immunologically and pre-C and pre-S sequences of HBV DNA in sera from several members of five...
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