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Article

Comparison of envelope and precore/core variants of hepatitis B virus (HBV) during chronic HBV infection.

Virology - 1 Sept 1993

Takayanagi M, Kakumu S, Ishikawa T, Higashi Y, Yoshioka K, Wakita T

Abstract excerpt

We analyzed entire pre-C/C and pre-S/S coding genes of hepatitis B virus (HBV) in serial serum samples from four chronic HBV carriers with 4-5 years of follow-up. Two patients with chronic active hepatitis became seronegative for HB e antigen (HBeAg), but the hepatitis did not subside, while the other two were persistent asymptomatic carriers with normal aminotransferase values. DNAs amplified by PCR were cloned...

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Identifiers

PMID: 8356791
DOI: 10.1006/viro.1993.1462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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