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Article

Clinical course and core variability in HBV infected patients without detectable anti-HBc antibodies.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2017

Anastasiou Olympia E, Widera Marek, Verheyen Jens, Korth Johannes, Gerken Guido, Helfritz Fabian A, Canbay Ali, Wedemeyer Heiner, Ciesek Sandra

Abstract excerpt

BACKGROUND: The presence of anti-HBc antibodies indicates direct encounter of the immune system with hepatitis B virus (HBV). OBJECTIVES: Aim of our study was to seek for anti-HBc negative but HBV replicating patients and analyze their clinical course and preconditions. STUDY DESIGN: From 1568 HBV-DNA positive patients, 29 patients (1.85%) tested negative for anti-HBc. The absence of anti-HBc could be confirmed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28622640
DOI: 10.1016/j.jcv.2017.06.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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