Article
High genomic variability in the pre-C region of hepatitis B virus in anti-HBe, HBV DNA-positive chronic hepatitis.
Journal of medical virology - 1 Aug 1990
Fiordalisi G, Cariani E, Mantero G, Zanetti A, Tanzi E, Chiaramonte M, Primi D
Abstract excerpt
Some chronic HBV carriers have circulating HBV DNA despite the presence of anti-HBeAg antibodies. This observation has recently been related to the presence, in the HBV pre-C region, of a translational stop codon that prevents HBeAg synthesis. In the present study, we analyzed, at the nucleotide...
Topics
- Base Sequence
- Chronic Disease
- DNA, Viral
- Female
- Genetic Variation
- Hepatitis B
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Open Reading Frames
- Polymerase Chain Reaction