Article
Hepatitis B virus genomes that cannot synthesize pre-S2 proteins occur frequently and as dominant virus populations in chronic carriers in Italy.
Virology - 1 Jun 1992
Santantonio T, Jung M C, Schneider R, Fernholz D, Milella M, Monno L, Pastore G, Pape G R, Will H
Abstract excerpt
The heterogeneity of hepatitis B virus (HBV) pre-S sequences coding for envelope proteins was tested by DNA amplification and direct sequencing of viral genomes from sera of 22 unselected chronic carriers resident in Southern Italy. The sequences of the dominant viral genome populations from 15 c...
Topics
- Amino Acid Sequence
- Base Sequence
- Carrier State
- DNA, Viral
- Female
- Genes, Viral
- Hepatitis B
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Humans
- Italy
- Male
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides