Article
Different prevalence of precore mutants in five members of a hepatitis-B-virus-infected family: evidence for a precore variant type in an asymptomatic anti-HBs patient.
Journal of hepatology - 1 Nov 1994
Barlet V, Zarski J P, Thelu M A, Bichard P, Seigneurin J M
Abstract excerpt
Chronic active hepatitis B (CAH-B), anti-HBe (+) has been associated with a hepatitis B virus variant carrying a stop codon at the distal pre-C region that prevents HBeAg synthesis. We analyzed the HBV DNA pre-C region in five members of a Turkish family. The mother presented an anti-HBe (+) CAH-...
Topics
- Adolescent
- Adult
- Base Sequence
- Blotting, Southern
- Cloning, Molecular
- Female
- Hepatitis Antibodies
- Hepatitis B
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Recombination, Genetic