Article
[p53 mutations and HPV infections in squamous epithelial carcinomas of the head-neck region. Long-term follow-up].
Mund-, Kiefer- und Gesichtschirurgie : MKG - 1 Jan 1998
Riethdorf S, Friedrich R E, Sühwold J, Ostwald C, Barten M, Gogacz P, Gundlach K K, Schlechte H, Becker J, Bregenzer T, Riethdorf L, Löning T
Abstract excerpt
Mutations of the p53 gene are the most commonly observed genetic alterations in malignant tumors and are often associated with a loss of the tumor suppressor function of the p53 protein. We have analyzed specimens of head and neck squamous cell carcinomas (HNSCC) from 110 patients for p53 gene mu...
Topics
- Adult
- Aged
- Carcinoma, Squamous Cell
- Cell Transformation, Neoplastic
- Female
- Follow-Up Studies
- Head and Neck Neoplasms
- Humans
- Lymph Nodes
- Lymphatic Metastasis
- Male
- Middle Aged
- Mutation
- Neoplasm Staging