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Article

A novel loss-of-function mutation in TP53 in an endometrial cancer cell line and uterine papillary serous carcinoma model.

Molecular and cellular biochemistry - 1 Mar 2007

Liu Zhihe, Wan Guanghua, Heaphy Christopher, Bisoffi Marco, Griffith Jeffrey K, Hu Chien-An A

Abstract excerpt

The etiology of carcinoma of the uterine endometrium (ECa) is poorly understood. However, loss of apoptosis is one of the major factors that allow cancer cells to survive and progress. Hec50co, a poorly differentiated human ECa cell line, is widely used in the investigation of ECa. Previously, Hec50co xenograft tumor model in nude mice developed an advanced phenotype, similar to that of uterine papillary serous...

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PMID: 17119852
DOI: 10.1007/s11010-006-9345-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel loss-of-function mutation in TP53 in an endometrial cancer cell line and uterine papillary serous carcinoma model.PMID 17119852Read ↗

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Establishment and characterization of two cell lines (HEC-155, HEC-180) derived from uterine papillary serous adenocarcinoma.Semantic proximity Read ↗

Loss of p53 function in uterine papillary serous carcinoma.Semantic proximity Read ↗

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