Article
Analysis of the p53 gene in human choriocarcinoma cell lines.
British journal of cancer - 1 Jan 1995
Yaginuma Y, Yamashita T, Takuma N, Katayama H, Ishikawa M
Abstract excerpt
In the present study, we analysed human choriocarcinoma cell lines for abnormalities in the tumour-suppressor gene p53 by Southern blotting, Northern blotting, non-radioisotopic single-stranded conformational polymorphism (SSCP) and complementary DNA sequencing. In all cell lines (Bewo, GCH-1, GCH-2, SCH, JAR, JEG-3, NUC-1 and HCCM-5), no p53 gene abnormality was detected by using Southern blotting. p53 mRNA of...
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