Article
Binding and repression of the latency-associated promoter of herpes simplex virus by the immediate early 175K protein.
The Journal of general virology - 1 Apr 1994
Batchelor A H, Wilcox K W, O'Hare P
Abstract excerpt
We demonstrate that the immediate early 175K protein (IE175K) of herpes simplex virus type 1 binds to the cap site of the latency-associated promoter (LAP) in an unusual manner. The complex formed on the LAP cap site was significantly larger than that formed on the IE175K cap site and the requirements for binding were qualitatively distinct with respect to both the primary sequence determinants at the site, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
