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Article

Transactivation of the major capsid protein gene of herpes simplex virus type 1 requires a cellular transcription factor.

Journal of virology - 1 Jul 1992

Chen S, Mills L, Perry P, Riddle S, Wobig R, Lown R, Millette R L

Abstract excerpt

The purpose of this investigation was to identify and characterize the regulatory elements involved in the transcriptional activation of the beta gamma (leaky-late or gamma 1) genes of herpes simplex virus type 1 (HSV-1) by using the major capsid protein (VP5 or ICP5) gene as model. Gel mobility shift assays with nuclear extracts from uninfected and infected HeLa cells enabled us to identify two major protein-DNA...

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Identifiers

PMID: 1318406
DOI: 10.1128/JVI.66.7.4304-4314.1992
PMCID: PMC241236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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