Article
Transactivation of the major capsid protein gene of herpes simplex virus type 1 requires a cellular transcription factor.
Journal of virology - 1 Jul 1992
Chen S, Mills L, Perry P, Riddle S, Wobig R, Lown R, Millette R L
Abstract excerpt
The purpose of this investigation was to identify and characterize the regulatory elements involved in the transcriptional activation of the beta gamma (leaky-late or gamma 1) genes of herpes simplex virus type 1 (HSV-1) by using the major capsid protein (VP5 or ICP5) gene as model. Gel mobility...
Topics
- Base Sequence
- Binding Sites
- Binding, Competitive
- Capsid
- Capsid Proteins
- DNA, Viral
- HeLa Cells
- Humans
- Immediate-Early Proteins
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
