Article

Genomic location dictates lytic promoter activity during herpes simplex virus latency

2023-12-06

Abstract excerpt

Herpes simplex virus 1 (HSV-1) is a significant pathogen that establishes life-long latent infections with intermittent episodes of resumed disease. In mouse models of HSV infection, persistent low-level lytic gene expression has been detected during latency in the absence of spontaneous reactivation events leading to new virus production. This viral activity during latency has been reported using a sensitive Cre-...

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Literature Corpus work: ef3795c3-5ca3-5e32-988a-ffe0f7a52a62
DOI: 10.1101/2023.12.05.570201

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