Article
A prominent serine-rich region in Vmw175, the major transcriptional regulator protein of herpes simplex virus type 1, is not essential for virus growth in tissue culture.
The Journal of general virology - 1 Aug 1990
Paterson T, Everett R D
Abstract excerpt
Herpes simplex virus type 1 (HSV-1) encodes five immediate early (IE) genes of which at least three are involved in the transcriptional regulation of later classes of viral genes. Perhaps the most important of these regulatory proteins is Vmw175, a nuclear phosphoprotein of 1298 predicted amino a...
Topics
- Amino Acid Sequence
- Cell Line
- Cloning, Molecular
- DNA-Binding Proteins
- Gene Expression Regulation, Viral
- Immediate-Early Proteins
- Molecular Sequence Data
- Mutation
- Restriction Mapping
- Sequence Homology, Nucleic Acid
- Serine