Article
Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement.
Endocrinology - 1 Apr 1994
Williams G R, Zavacki A M, Harney J W, Brent G A
Abstract excerpt
Thyroid hormone receptor (T3R)-accessory protein heterodimers preferentially bind to thyroid hormone response elements (TREs), which contain hexamer domains arranged as a direct repeat separated by a 4-basepair gap (DR + 4). T3R homodimers, however, preferentially bind to elements that consist of...
Topics
- Animals
- Base Sequence
- Binding, Competitive
- Chickens
- Molecular Sequence Data
- Muramidase
- Mutation
- Receptors, Thyroid Hormone
- Triiodothyronine