Article
Functional and structural role of a tryptophan generally observed in protein-carbohydrate interaction. TRP-62 of hen egg white lysozyme.
The Journal of biological chemistry - 11 Mar 1994
Maenaka K, Kawai G, Watanabe K, Sunada F, Kumagai I
Abstract excerpt
In order to elucidate the role of the aromatic ring in recognition of the sugar ring, Trp-62 of hen egg white lysozyme, which is proposed on the basis of x-ray crystallography data to make contact with a sugar ring through van der Waals interaction, was replaced with aliphatic amino acids (Leu, I...
Topics
- Animals
- Binding Sites
- Carbohydrate Metabolism
- Carbohydrate Sequence
- Chickens
- Glycine
- Magnetic Resonance Spectroscopy
- Muramidase
- Mutation
- Protein Conformation
- Tryptophan