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Article

Structural analysis of mutant hen egg-white lysozyme preferring a minor binding mode.

Biochimica et biophysica acta - 23 Apr 1998

Maenaka K, Matsushima M, Kawai G, Watanabe K, Kuroki R, Kumagai I

Abstract excerpt

Trp62 in hen egg-white lysozyme has general features observed in protein-carbohydrate interactions, a stacking interaction toward nonpolar surface of the substrate sugar residue B and a hydrogen bonding network with the residue C. Our previous report (I. Kumagai, K. Maenaka, F. Sunada, S. Takeda, K. Miura, Eur. J. Biochem. 212 (1993) 151-156.) showed that the substitution of Trp62 changed the substrate binding...

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PMID: 9602036
DOI: 10.1016/s0167-4838(97)00199-4

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Structural analysis of mutant hen egg-white lysozyme preferring a minor binding mode.PMID 9602036Read ↗

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