Article
D-penicillamine- and quinidine-induced antinuclear antibodies in A.SW (H-2s) mice: similarities with autoantibodies in spontaneous and heavy metal-induced autoimmunity.
European journal of immunology - 1 Mar 1994
Monestier M, Novick K E, Losman M J
Abstract excerpt
Ten percent of human lupus syndromes occur in patients as a result of treatment with certain medications. H-2s mice can produce autoantibodies following treatment with various drugs or heavy metals and they are a potential animal model of drug-induced lupus. We have examined nine anti-chromatin m...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Antinuclear
- Antibodies, Monoclonal
- Antibody Specificity
- Autoimmune Diseases
- Base Sequence
- Female
- Gene Expression
- Genes, Immunoglobulin
- Immunoglobulin Heavy Chains
- Immunoglobulin Variable Region
- Immunoglobulin kappa-Chains
- Mice
- Mice, Inbred A
- Molecular Sequence Data
- Mutation
- Penicillamine