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Article

Effect of histone and histone-RNA complexes on the disease process of murine systemic lupus erythematosus.

Autoimmunity - 1 Jan 1995

Ravirajan C T, Muller S, Katz D R, Isenberg D A

Abstract excerpt

Systemic lupus erythematosus (SLE) is characterised by the production of a variety of autoantibodies against cell surface, nuclear and cytoplasmic antigens. The antigen or antigens responsible for the induction of this disease is/are unknown. We have analysed the antigenicity and pathogenicity of free histones and histones complexed with RNA in Balb/c, B10 Br, C57BL/6 and MRL-lpr/lpr mice by giving 1 microgram...

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PMID: 8679899
DOI: 10.3109/08916939508993358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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