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Article

D-penicillamine-induced autoantibodies in a mouse model.

Clinical and experimental rheumatology - 1 Jan 2000

Brik R, Tenenbaum G, Blank M, Shoenfeld Y, Barzilai D, Bloch K, Vardi P

Abstract excerpt

OBJECTIVE: We have previously shown that the administration of D-penicillamine (D-PEN) to patients with rheumatoid arthritis induces circulating insulin autoantibodies (INSAAB). In order to gain further insight into such immune responses, we measured a battery of circulating autoantibodies in 4 strains of mice receiving D-PEN: C57BL/KsJ, BALB/c, C3H/HeJ, and C57BL/6. These rodents groups differ in their degree of...

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PMID: 7586781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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