Retinoblastoma gene mutations in primary human bladder cancer.

doi:10.1038/bjc.1995.160

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Article

Retinoblastoma gene mutations in primary human bladder cancer.

British journal of cancer - 1 Apr 1995

Miyamoto H, Shuin T, Torigoe S, Iwasaki Y, Kubota Y

Abstract excerpt

Inactivation of the retinoblastoma (RB) gene is known to be implicated in the pathogenesis of several types of human cancers. Since structural alterations of the RB gene have not been well examined in human bladder cancer, we looked for mutations in the entire coding region of this gene using pol...

Topics

Aged
Base Sequence
Codon
DNA Primers
DNA, Neoplasm
Exons
Female
Genes, Retinoblastoma
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Neoplasm Staging
Point Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Promoter Regions, Genetic

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