Identification of polypeptides whose presence correlates with retention or loss of an albumin extinguisher chromosome in rat hepatoma-mouse L cell fibroblast microcell hybrids.

Abstract excerpt

The total protein content of a series of hybrids derived from the fusion of rat hepatoma cells with microcells of mouse L cell fibroblasts has been evaluated by two-dimensional electrophoresis. The parental rat hepatoma cells express a large set of hepatic functions, including the production of albumin. In the microcell hybrids containing chromosome M1 (marker 1) as the unique mouse chromosome, it has been...

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