Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tissue-specific extinguisher loci in the murine genome: a screening study based on a rat/mouse microcell hybrid panel.

Somatic cell and molecular genetics - 1 May 1994

Schafer A J, Bulla G A, Fournier R E

Abstract excerpt

Extinction of tissue-specific traits in intertypic somatic cell hybrids is a well-known phenomenon. In the past few years, microcell hybrids have been used in attempts to dissect this phenotype genetically, and tissue-specific extinguisher loci have been mapped to two different mouse chromosomes....

Topics

Animals
Cells, Cultured
Chromosomes
Gene Expression
Genomic Library
Humans
Hybrid Cells
Karyotyping
Liver
Mice
Phenotype
Phosphoenolpyruvate Carboxykinase (GTP)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Rats

Translocation, Genetic

Tumor Cells, Cultured

Source

Identifiers

PMID: 7940021
DOI: 10.1007/BF02254760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7940021-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tissue-specific extinguisher loci in the murine genome: a screening study based on a rat/mouse microcell hybrid panel.PMID 7940021Read ↗

Tissue-specific extinguisher loci in the human genome: a screening study based on random marking and transfer of human chromosomes.Semantic proximity Read ↗

Extinction of albumin gene expression in a panel of human chromosome 2 microcell hybrids.Semantic proximity Read ↗

Extinction of alpha 1-antitrypsin gene expression in somatic cell hybrids: evidence for multiple controls.Semantic proximity Read ↗

Identification of polypeptides whose presence correlates with retention or loss of an albumin extinguisher chromosome in rat hepatoma-mouse L cell fibroblast microcell hybrids.Semantic proximity Read ↗

Constancy of expression of the protein kinase A regulatory subunit R1 alpha in hepatoma cell lines of different phenotypes.Semantic proximity Read ↗

Subtractive hybridization cloning of a tissue-specific extinguisher: TSE1 encodes a regulatory subunit of protein kinase A.Semantic proximity Read ↗

A facile method for somatic, lifelong manipulation of multiple genes in the mouse liverSemantic proximity Read ↗

Mouse A9 Cells Containing Single Human Chromosomes for Analysis of Genomic ImprintingSemantic proximity Read ↗

Two genetically defined trans-acting loci coordinately regulate overlapping sets of liver-specific genes.Semantic proximity Read ↗

Genetic analysis of a transcriptional activation pathway by using hepatoma cell variants.Semantic proximity Read ↗

Complete reconstitution of mouse liver with xenogeneic hepatocytes.Semantic proximity Read ↗

The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-dependent protein kinase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.