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Article

Tissue-specific extinguisher loci in the murine genome: a screening study based on a rat/mouse microcell hybrid panel.

Somatic cell and molecular genetics - 1 May 1994

Schafer A J, Bulla G A, Fournier R E

Abstract excerpt

Extinction of tissue-specific traits in intertypic somatic cell hybrids is a well-known phenomenon. In the past few years, microcell hybrids have been used in attempts to dissect this phenotype genetically, and tissue-specific extinguisher loci have been mapped to two different mouse chromosomes. When transferred from fibroblast into hepatoma cells by microcell fusion, these loci down-regulate expression of...

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PMID: 7940021
DOI: 10.1007/BF02254760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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