Article
Extinction of albumin gene expression in a panel of human chromosome 2 microcell hybrids.
Genomics - 1 Feb 1996
Cerosaletti K M, Fournier R E
Abstract excerpt
Expression of the serum albumin gene is extinguished in rat hepatoma microcell hybrids that retain mouse chromosome 1. These data define a trans-dominant extinguisher locus, Tse-2, on mouse chromosome 1. To localize the human TSE2 locus, we prepared and characterized rat/human microcell hybrids t...
Topics
- Animals
- Base Sequence
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 2
- DNA Primers
- Gene Expression
- Humans
- Hybrid Cells
- Liver
- Molecular Sequence Data
- Phenotype
- Rats
- Serum Albumin
- Tumor Cells, Cultured