Article
Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas.
Journal of surgical oncology - 1 Feb 1994
Hoshi T, Imai M, Ogawa K
Abstract excerpt
Mucin-producing tumors of the pancreas (MPT) are characterized by the production of much mucin and a benign course after surgical treatment. We examined 16 cases of MPT and 20 cases of "common" pancreatic duct cell carcinomas (DCC) in regard to K-ras and p53 mutations. The mutations were detected by constant denaturant gel electrophoresis in combination with other techniques using PCR products amplified from the...
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