Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas.

doi:10.1002/jso.2930550205

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Article

Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas.

Journal of surgical oncology - 1 Feb 1994

Hoshi T, Imai M, Ogawa K

Abstract excerpt

Mucin-producing tumors of the pancreas (MPT) are characterized by the production of much mucin and a benign course after surgical treatment. We examined 16 cases of MPT and 20 cases of "common" pancreatic duct cell carcinomas (DCC) in regard to K-ras and p53 mutations. The mutations were detected...

Topics

Adenocarcinoma, Mucinous
Adenoma
Adult
Aged
Aged, 80 and over
Base Sequence
Carcinoma, Intraductal, Noninfiltrating
Female
Genes, p53
Genes, ras
Humans
Male
Middle Aged
Molecular Sequence Data
Mucins
Mutation
Pancreatic Neoplasms
Polymerase Chain Reaction

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