Article
K-ras gene mutations and loss of heterozygosity at the p53 gene locus relative to histological characteristics of mucin-producing tumors of the pancreas.
Human pathology - 1 Jul 2000
Sakai Y, Yanagisawa A, Shimada M, Hidaka E, Seki M, Tada Y, Harada T, Saisho H, Kato Y
Abstract excerpt
Mucin-producing tumors (MPTs) of the pancreas accompanied by carcinomas usually include various grades of dysplasia in the ductal epithelium, and invasive areas are histologically similar to those of common invasive ductal carcinomas, suggesting that MPTs provide a good tool to investigate early stages of pancreatic carcinogenesis. Thus, to clarify genetic alterations in the early stage of pancreatic...
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