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Article

p53 protein overexpression and K-ras codon 12 mutation in pancreatic ductal carcinoma: correlation with histologic factors.

Pathology international - 1 Aug 1997

Kasuya K, Watanabe H, Nakasako T, Ajioka Y, Koyanagi Y

Abstract excerpt

The correlation of p53 protein overexpression and the K-ras codon 12 mutation with histologic type, grade of cytologic atypia, depth of invasion and other histologic prognostic factors was studied in paraffin sections from 43 ductectatic- and 70 solid-type pancreatic ductal carcinomas. Overexpression of p53 was found in 23.3% (10/43) of ductectatic carcinomas (17.2% of intraductal and 35.7% of invasive...

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Identifiers

PMID: 9293533
DOI: 10.1111/j.1440-1827.1997.tb04536.x

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