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Article

K-ras and Dpc4 mutations in chronic pancreatitis: case series.

Croatian medical journal - 1 Apr 2007

Popović Hadzija Marijana, Korolija Marina, Jakić Razumović Jasminka, Pavković Pajica, Hadzija Mirko, Kapitanović Sanja

Abstract excerpt

AIM: To assess whether alterations in the K-ras, p53, and DPC4 genes are present in pancreatitis, a potential precancerous condition that can progress to pancreatic adenocarcinoma. To investigate the alterations occurring at hot spots of K-ras (exon 1), p53 (exons 5 and 7), and DPC4 (exons 8, 10 and 11). METHODS: In 10 patients with acute and 22 with chronic pancreatitis, without pancreatic intraepithelial...

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PMID: 17436386
PMCID: PMC2080529

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