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Article

K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions.

Cancer research - 15 Mar 1994

Pellegata N S, Sessa F, Renault B, Bonato M, Leone B E, Solcia E, Ranzani G N

Abstract excerpt

We studied K-ras and p53 gene mutations in a panel of 57 primary pancreatic cancers including ductal and nonductal tumors. DNAs were obtained from formalin-fixed, paraffin-embedded material. Target sequences were amplified by polymerase chain reaction and analyzed by denaturing gradient gel elect...

Topics

Carcinoma, Ductal, Breast
DNA, Neoplasm
Electrophoresis
Exons
Formaldehyde
Genes, p53
Genes, ras
Humans
Mutation
Pancreatic Neoplasms
Paraffin Embedding
Polymerase Chain Reaction

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Identifiers

PMID: 8137263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8137263-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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