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Article

Pancreatic adenocarcinomas frequently show p53 gene mutations.

The American journal of pathology - 1 May 1993

Scarpa A, Capelli P, Mukai K, Zamboni G, Oda T, Iacono C, Hirohashi S

Abstract excerpt

Thirty-four pancreatic adenocarcinomas were studied for the presence of p53 gene mutations by the single-strand conformation polymorphism method and by direct sequencing of PCR-amplified fragments. p53 protein expression was immunohistochemically evaluated using monoclonal PAb1801 and polyclonal...

Topics

Adenocarcinoma
Adult
Aged
Base Sequence
Cell Nucleus
Female
Humans
Immunohistochemistry
Male
Middle Aged
Molecular Sequence Data
Mutation
Oligonucleotide Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pancreatic Neoplasms

Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 8494051
PMCID: PMC1886920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8494051-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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