Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T cell recognition of beryllium.

Current opinion in immunology - 1 Dec 2013

Dai Shaodong, Falta Michael T, Bowerman Natalie A, McKee Amy S, Fontenot Andrew P

Abstract excerpt

Chronic beryllium disease (CBD) is a granulomatous lung disorder caused by a hypersensitivity to beryllium and characterized by the accumulation of beryllium-specific CD4(+) T cells in the lung. Genetic susceptibility to beryllium-induced disease is strongly associated with HLA-DP alleles possessing a glutamic acid at the 69th position of the β-chain (βGlu69). The structure of HLA-DP2, the most prevalent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4-Positive T-Lymphocytes
Share to Chronic Disease
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 23978481
DOI: 10.1016/j.coi.2013.07.012
PMCID: PMC3883670

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T cell recognition of beryllium.PMID 23978481Read ↗

Metal-specific CD4+ T-cell responses induced by beryllium exposure in HLA-DP2 transgenic mice.Semantic proximity Read ↗

T cell recognition in chronic beryllium disease.Semantic proximity Read ↗

Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation.Semantic proximity Read ↗

HLA-DP allele-specific T cell responses to beryllium account for DP-associated susceptibility to chronic beryllium disease.Semantic proximity Read ↗

Crystal structure of HLA-DP2 and implications for chronic beryllium disease.Semantic proximity Read ↗

Immunologic Effects of Beryllium Exposure.Semantic proximity Read ↗

Chronic beryllium disease: T cell recognition of a metal presented by HLA-DP.Semantic proximity Read ↗

Chronic beryllium disease: immune-mediated destruction with implications for organ-specific autoimmunity.Semantic proximity Read ↗

Beryllium presentation to CD4+ T cells is dependent on a single amino acid residue of the MHC class II beta-chain.Semantic proximity Read ↗

Impact of negatively charged patches on the surface of MHC class II antigen-presenting proteins on risk of chronic beryllium disease.Semantic proximity Read ↗

Recent advances in understanding the biomolecular basis of chronic beryllium disease: a review.Semantic proximity Read ↗

Beryllium presentation to CD4+ T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.