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Article

Genetic susceptibility and immune-mediated destruction in beryllium-induced disease.

Trends in immunology - 1 Oct 2005

Fontenot Andrew P, Maier Lisa A

Abstract excerpt

Chronic beryllium disease (CBD) is a hypersensitivity disorder caused by beryllium exposure in the workplace and is characterized by the accumulation of beryllium-specific CD4(+) T cells in the lung and granulomatous inflammation. This disorder occurs in 2-16% of exposed workers, depending on genetic susceptibility and the nature of the exposure. Susceptibility has been associated with HLA-DP alleles possessing a...

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Identifiers

PMID: 16099719
DOI: 10.1016/j.it.2005.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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