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Article

Expression of an mdr gene is associated with a new form of resistance to dexamethasone-induced apoptosis.

Molecular endocrinology (Baltimore, Md.) - 1 Jul 1993

Bourgeois S, Gruol D J, Newby R F, Rajah F M

Abstract excerpt

A variant, MS23, of murine thymoma W7 cells, previously selected for its resistance to low concentrations of dexamethasone, is cross-resistant to unrelated drugs such as puromycin and colchicine. We report here that transcription of the mouse mdr1 gene is activated and P-glycoprotein is expressed in MS23 cells. Moreover, additional variants with increased resistance to dexamethasone and other drugs can be...

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PMID: 8105374
DOI: 10.1210/mend.7.7.8105374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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