Article
Cloning of glucocorticoid-regulated genes in C6/ST1 rat glioma phenotypic reversion.
The Journal of endocrinology - 1 Jan 1996
Valentini S R, Armelin M C
Abstract excerpt
The C6 rat glioma cell line is response to glucocorticoid hormones. C6 variants that are hyper-responsive (ST1) and resistant (P7) to hormone treatment have been derived previously. Glucocorticoid treatment of ST1 cells leads to complete reversion of the transformed phenotype and loss of tumorigenic potential. Production of C type retrovirus particles is also induced by glucocorticoids in ST1 cells. Cloning of...
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