The distorted alpha 2-adrenoceptor genotype distribution in F2 populations of Dahl salt sensitive and resistant rats cross.

doi:10.1016/0024-3205(93)90760-z

Back to search

Article

The distorted alpha 2-adrenoceptor genotype distribution in F2 populations of Dahl salt sensitive and resistant rats cross.

Life sciences - 1 Jan 1993

Sun L, Chun M, McArdle S, Kimberling W, Pettinger W

Abstract excerpt

To examine the role of the alpha 2-adrenoceptor gene in the development of genetic hypertensive rats, we tested Dahl salt sensitive (S) and resistant rats (R) for the presence of a restriction fragment length polymorphism (RFLP) in that gene. An RFLP was found between the S and R rats with a huma...

Topics

Animals
Blotting, Southern
Chi-Square Distribution
Crosses, Genetic
Female
Genotype
Homozygote
Male
Polymorphism, Restriction Fragment Length
Rats
Rats, Inbred SHR
Rats, Inbred Strains
Receptors, Adrenergic, alpha

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.