Article
Apolipoprotein E epsilon 4 allele in Alzheimer's disease and vascular dementia.
Dementia (Basel, Switzerland) - 1 Jan 2000
Frisoni G B, Calabresi L, Geroldi C, Bianchetti A, D'Acquarica A L, Govoni S, Sirtori C R, Trabucchi M, Franceschini G
Abstract excerpt
The frequency of the epsilon 4 allele of the apolipoprotein E (apoE) is increased in familial and sporadic late-onset Alzheimer's disease, but its prevalence in non-Alzheimer dementias in Caucasian populations is unknown. We found that the frequency of the apoE epsilon 4 allele was 0.45 in 93 Alzheimer's disease patients, 0.46 in 23 vascular dementia patients, 0.31 in 13 dementia of the frontal type patients, and...
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