Article
Allelic deletion mapping of putative tumor suppressor genes on 17q in sporadic ovarian cancer.
Journal of obstetrics and gynaecology (Tokyo, Japan) - 1 Dec 1995
Chen K C, Hsieh T T, Schwartz P E, Yang-Feng T L
Abstract excerpt
OBJECTIVES: 1) To study whether the same or different chromosome 17q genes may be involved in the oncogenesis of familial and sporadic ovarian malignancies. 2) To localize the candidate gene in the sporadic ovarian cancers. METHODS (STUDY DESIGN): Using DNA extracted from ovarian tumors and corresponding peripheral leukocyte, we examined the status of loss of heterozygosity (LOH) at 12 loci spanning chromosome...
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