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Article

Allelotyping defines minimal imbalance at chromosomal region 17q25 in non-serous epithelial ovarian cancers.

Oncogene - 9 Mar 2000

Dion F, Mes-Masson A M, Seymour R J, Provencher D, Tonin P N

Abstract excerpt

Allelic deletions of multiple chromosome 17q loci in sporadic ovarian cancer of epithelial origin suggest that inactivation of tumor suppressor gene(s) in these regions may be important for ovarian tumorigenesis. To further define the pattern of allelic imbalance in epithelial ovarian tumors of different histologies, a PCR-based assay was used to assess loss of heterozygosity (LOH) of polymorphic markers...

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Share to Carcinoma
Share to Carcinoma, Endometrioid
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cystadenocarcinoma, Serous

Share to Loss of Heterozygosity

Share to Neoplasm Staging

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Source

Identifiers

PMID: 10723138
DOI: 10.1038/sj.onc.1203463

Genes

BRCA1
GH1
NME1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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