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Article

MHC-extended haplotypes in families of patients with Graves' disease.

Human immunology - 1 Feb 1993

Ratanachaiyavong S, Lloyd L, Darke C, McGregor A M

Abstract excerpt

MHC-extended haplotypes were investigated in multiplex families of patients with hyperthyroid GD. Using a combination of both phenotypic (serology and protein electrophoresis) and genotypic (DNA-RFLP) markers, 159 MHC-extended haplotypes extending from HLA-A across the MHC class III (C2, Bf, C4A, and C4B) toward the HLA-DR/DQ complex were deduced from 217 (51 and 166 affected and unaffected) members of 21...

Topics

Adult
Autoantibodies
Complement C4
Female
Genotype
Graves Disease
Haplotypes
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
Immunophenotyping
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Major Histocompatibility Complex

Male

Middle Aged

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 8096501
DOI: 10.1016/0198-8859(93)90112-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8096501-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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