Article
Human histocompatibility leukocyte antigen-DQA1*0501 allele associated with genetic susceptibility to Graves' disease in a Caucasian population.
The Journal of clinical endocrinology and metabolism - 1 Jun 1993
Yanagawa T, Mangklabruks A, Chang Y B, Okamoto Y, Fisfalen M E, Curran P G, DeGroot L J
Abstract excerpt
Graves' disease (GD) is an autoimmune disease of the thyroid gland. Genes of, or closely associated to, the HLA complex are assumed to contribute to the genetic predisposition to GD. We have previously reported an increased frequency of HLA-DR3/DQ2 in Caucasian patients with GD, and recently the importance of Dw24 encoded by DRB3 gene has been suggested. To further investigate the associations of GD and these...
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