Article
Certain HLA alleles are associated with stress-triggered Graves' disease and influence its course.
Endocrine - 1 Jan 2017
Vita Roberto, Lapa Daniela, Trimarchi Francesco, Vita Giuseppe, Fallahi Poupak, Antonelli Alessandro, Benvenga Salvatore
Abstract excerpt
There are no studies on HLA analysis in patients in whom Graves' disease (GD) hyperthyroidism has been preceded by ≥1 stressful event. The aim of the present study was to identify predisposing or protecting HLA alleles and their effects on the course of GD in this subset of patients. We performed serological HLA typing in 58 Caucasian patients with stress-related GD and in 130 matched healthy controls (HC). We...
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