Article
HLA-DRB3 gene alleles in Caucasian patients with Graves' disease.
The Clinical investigator - 1 Oct 1992
Boehm B O, Kühnl P, Manfras B J, Chen M, Lee J C, Holzberger G, Seidl S, Schifferdecker E, Schumm-Draeger P M, Usadel K H
Abstract excerpt
Graves' disease (GD) is a human leukocyte antigen (HLA) linked organ-specific autoimmune disease. In German GD patients the disease is associated with HLA specificities of the HLA-DRw52 family (HLA-DR3, -DR5, and DR6; HLA-DRB3 positive HLA haplotypes). Recently, a strong association with a HLA-DR...
Topics
- Alleles
- Base Sequence
- Biomarkers
- DNA
- Graves Disease
- HLA-DR Antigens
- HLA-DRB3 Chains
- Heterozygote
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Retrospective Studies
- Risk Factors
- Serologic Tests
- White People