Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fine mapping MHC associations in Graves' disease and its clinical subtypes in Han Chinese.

Journal of medical genetics - 1 Oct 2018

Chu Xun, Yang Minjun, Song Zhen-Ju, Dong Yan, Li Chong, Shen Min, Zhu Yong-Qiang, Song Huai-Dong, Chen Sai-Juan, Chen Zhu, Huang Wei

Abstract excerpt

BACKGROUND: The classical human leucocyte antigen (HLA) genes were the most important genetic determinant for Graves' disease (GD). The aim of the study was to fine map causal variants of the HLA genes. METHODS: We applied imputation with a Pan-Asian HLA reference panel to thoroughly investigate themajor histocompatibility complex (MHC) associations with GD down to the amino acid level of classical HLA genes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Graves Disease

Share to Linkage Disequilibrium

Share to Major Histocompatibility Complex

Share to Models, Molecular

Share to Phosphoproteins

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 29987165
DOI: 10.1136/jmedgenet-2017-105146
PMCID: PMC6161647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine mapping MHC associations in Graves' disease and its clinical subtypes in Han Chinese.PMID 29987165Read ↗

Analysis of HLA Variants and Graves' Disease and Its Comorbidities Using a High Resolution Imputation System to Examine Electronic Medical Health Records.Semantic proximity Read ↗

Identification of independent risk loci for Graves' disease within the MHC in the Japanese population.Semantic proximity Read ↗

Comprehensive genotyping in two homogeneous Graves' disease samples reveals major and novel HLA association alleles.Semantic proximity Read ↗

A dense mapping study of six European AITD susceptibility regions in a large Chinese Han Cohort of Graves' disease.Semantic proximity Read ↗

The genetics of Graves' disease.Semantic proximity Read ↗

Meta-Analysis of CTLA-4 +49 Gene Polymorphism and Susceptibility to Graves' Disease.Semantic proximity Read ↗

Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.Semantic proximity Read ↗

A refined study of FCRL genes from a genome-wide association study for Graves' disease.Semantic proximity Read ↗

The genetics of Graves' disease.Semantic proximity Read ↗

Genome-wide scan of Graves' disease: evidence for linkage on chromosome 5q31 in Chinese Han pedigrees.Semantic proximity Read ↗

The HLA-DRB1 gene and Graves disease in Taiwanese children: a case-control and family-based study.Semantic proximity Read ↗

The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.