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Article

Paraffin wax-embedded material as a source of DNA for the detection of somatic genetic changes.

The Journal of pathology - 1 Jan 1993

Sundaresan V, Ganly P, Hasleton P, Bleehen N M, Rabbitts P

Abstract excerpt

Loss of genetic material, corresponding to chromosomal deletions, has been detected in a wide range of tumours and may indicate the position of a tumour suppressor gene. In order to identify the position of such a gene more precisely, many tumour samples must be studied until a minimum consensus deletion is characterized. This process is particularly necessary for lung tumours in which the deletion in chromosome...

Topics

Alleles
Carcinoma, Non-Small-Cell Lung
Chromosome Deletion
Chromosomes, Human, Pair 3
DNA, Neoplasm
Genotype
Humans
Lung Neoplasms
Paraffin Embedding
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8094433
DOI: 10.1002/path.1711690108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8094433-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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