Article
Paraffin wax-embedded material as a source of DNA for the detection of somatic genetic changes.
The Journal of pathology - 1 Jan 1993
Sundaresan V, Ganly P, Hasleton P, Bleehen N M, Rabbitts P
Abstract excerpt
Loss of genetic material, corresponding to chromosomal deletions, has been detected in a wide range of tumours and may indicate the position of a tumour suppressor gene. In order to identify the position of such a gene more precisely, many tumour samples must be studied until a minimum consensus deletion is characterized. This process is particularly necessary for lung tumours in which the deletion in chromosome...
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