Article
Somatic genetic changes in lung cancer and precancerous lesions.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 1995
Sundaresan V, Heppell-Parton A, Coleman N, Miozzo M, Sozzi G, Ball R, Cary N, Hasleton P, Fowler W, Rabbitts P
Abstract excerpt
BACKGROUND: Morphological abnormalities of the bronchial epithelium are associated with lung cancer development and are considered likely to represent the preneoplastic stage of the disease. The association of these lesions with different histological types of lung cancer was reviewed in a series...
Topics
- Bronchi
- Bronchial Neoplasms
- Carcinoma, Squamous Cell
- Chromosomes, Human, Pair 3
- Genes, p53
- Genes, ras
- Genotype
- Heterozygote
- Humans
- Karyotyping
- Lung
- Lung Neoplasms
- Precancerous Conditions
