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Article

In-depth analysis of molecular alterations within normal and tumour tissue from an entire bronchial tree.

International journal of oncology - 1 Mar 2003

Sikkink Stephen K, Liloglou Triantafillos, Maloney Paul, Gosney John R, Field John K

Abstract excerpt

Using laser capture microdissection (LCM), fluorescent microsatellite analysis and immunohistochemical analysis, we have constructed a detailed topographical molecular map of the entire bronchial tree surrounding a primary bronchial squamous carcinoma in order to establish the relationship between the molecular damage within the airway and that in the tumour itself. Allelic imbalance was analysed using markers on...

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PMID: 12579312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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