Article
A submicroscopic homozygous deletion at the D3S3 locus in a cell line isolated from a small cell lung carcinoma.
Genes, chromosomes & cancer - 1 Sept 1990
Rabbitts P, Bergh J, Douglas J, Collins F, Waters J
Abstract excerpt
We have used 14 DNA probes, which detect 19 different restriction enzyme length polymorphisms, to search for heterozygosity on chromosome 3 in five cell lines isolated from patients with small cell lung carcinoma. The cell lines on karyotype analysis did not show the deletion in chromosome 3 char...
Topics
- Alleles
- Blotting, Southern
- Carcinoma, Small Cell
- Cell Line
- Chromosome Deletion
- Chromosomes, Human, Pair 3
- DNA Probes
- DNA Restriction Enzymes
- DNA, Neoplasm
- Gene Library
- Homozygote
- Humans
- Karyotyping
- Lung Neoplasms
- Polymorphism, Restriction Fragment Length