Linkage of familial breast cancer to chromosome 17q21 may not be restricted to early-onset disease.

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Article

Linkage of familial breast cancer to chromosome 17q21 may not be restricted to early-onset disease.

American journal of human genetics - 1 Jun 1992

Margaritte P, Bonaiti-Pellie C, King M C, Clerget-Darpoux F

Abstract excerpt

Lod scores for linkage between familial breast and ovarian cancer and markers on chromosome 17q21 are more frequently positive among families with disease diagnosed at younger ages than they are among older-onset families, suggesting that linkage is restricted to early-onset disease. However, for...

Topics

Adult
Age Factors
Breast Neoplasms
Chromosome Banding
Chromosomes, Human, Pair 17
Diabetes Mellitus, Type 1
Female
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Genotype
Humans
Lod Score
Middle Aged
Probability
Risk Factors

Source

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Identifiers

PMID: 1598903
PMCID: PMC1682567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1598903-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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